Fri Aug 01 2025

20 articles - From Friday Jul 25 2025 to Friday Aug 01 2025

parm_toc.knit

Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

J Crohns Colitis

ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with IBD: Part 2.

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ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with Inflammatory Bowel Disease: Part 1.

It provides recommendations on requirements for initial diagnosis, detection of complications, the use of monitoring tools in patients with IBD and diagnostics in specific situations, such as pregnancy, postoperatively and for cancer surveillance. The guideline is a joint project of the European Crohn's and Colitis Organization (ECCO), the European Society of Gastrointestinal and Abdominal Radiology, the European Society of Pathology, and the International Bowel Ultrasonography Group under the leadership of ECCO.

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Meta-analysis

meta-analyses and systematic reviews

Liver Transpl

Incidence and risk factors for skin cancer in liver transplant recipients: A systematic review.

This study was limited by the heterogeneity of the study population, methods, and definitions of skin cancer. Overall, liver transplant recipients face heightened long-term risks of NMSCs, and while key risk factors are well established, there remains a gap in skin cancer surveillance and patient education within this population.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Circulating Bile Acids, Bile Acids Receptor Polymorphisms, and Risk of Chronic Kidney Disease among Individuals with Newly Diagnosed Type 2 Diabetes: A Prospective Study.

Among adults with T2D, higher concentrations of most circulating PBAs and total unconjugated SBAs were linearly associated with higher a risk of CKD, and genetic variations in FXR modified the association of unconjugated SBAs with CKD.

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Dietary patterns and risk of Alzheimer's disease and related dementias across five racial and ethnic groups in the Multiethnic Cohort Study.

Healthy dietary patterns in mid- to late-life and improvement in older age were associated with a reduced risk of ADRD in a diverse population. The racial and ethnic heterogeneity in the relationships observed warrants further study.

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Investigating the impact of body weight changes and blood lipids on the risk for mild cognitive impairment in Parkinson´s disease; a prospective cohort study.

High risk for MCI in patients with PD at the time of diagnosis was associated with low levels of P-TG and an interaction between change in BMI and P-TG before diagnosis, suggesting that nutritional factors have complex influence on cognitive function in the prodromal stage of PD.

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Modelled impacts of substituting meat and dairy with plant-based substitutes on the risk of nutrient deficiency and chronic disease mortality: a microsimulation study in French adults.

As modeled, full substitution of animal products with PBS would result in limited increases in deficiency risk, and decreases in chronic disease mortality, with meat replacement providing most of the benefits. Expected effects vary widely depending on the nutritional quality of the substitutes.

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The Interplay of Nutritional Status and Physical Function on Health Outcomes in Older Adults: A Longitudinal Study in Singapore.

Both nutritional status and physical function are independently and interactively associated with health outcomes in older adults. These findings underscore the need for integrated interventions targeting both nutritional status and physical function to promote healthy aging and reduce frailty. Future research should explore the mediating role of physical function and evaluate strategies to optimize health outcomes in older adults.

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The regulation of fatty acid mobilization is extravagant rather than frugal - a perspective indicating a limitation of the thrifty genotype hypothesis.

Experimental evidence suggests that a rising plasma FFA level worsens insulin resistance, and conversely, making FFA mobilization thriftier (slowing FFA mobilization) improves insulin sensitivity. It is concluded that fatty acid trafficking is inherently unthrifty, and that this lavish approach for regulating fat metabolism contributes to the high incidence of pre-diabetes and type 2 diabetes.

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Inflamm Bowel Dis

Efficacy and Safety of Ustekinumab and Vedolizumab for Crohn's Disease of the Pouch.

In one of the largest cohorts evaluating UST and VDZ for CD of the pouch thus far, these biologics were found to be safe and effective treatments for CD of the pouch.

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Preferences, Acceptability, and Utilization of Multimodal Self-Help Interventions in Adults With Inflammatory Bowel Diseases: A Pragmatic Multicenter Study With Patients and Clinicians.

Few patients with IBD use self-help resources, even though the majority regard multimodal self-help resources as acceptable and feasible to get information, find community and support, and manage living with IBD.

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Liver Transpl

A novel, institutionally developed hypothermic oxygenated machine PErfusion system allows low-cost, universal implementation for liver transplantation: A safety and feasibility pilot study.

The total cost of the COARO system is US$1,494.87 per LT, 80% cheaper than a commercial equivalent. The COARO system is safe and presents significant economic advantage over commercial systems, allowing universal implementation of HOPE for al LT procedures in under resourced units.

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Pancreas

Ancient and Modern History of Pancreatic Surgery.

In parallel, surgery for pancreatic adenocarcinoma was completed since the 90s by adjuvant chemotherapy then by neodadjuvant treatments, allowing more resections with a more favorable prognosis. More recently, islet cell transplantation, an alternative to pancreatic transplantation, and minimally invasive surgery have expanded the possibilities of less aggressive pancreatic surgery.

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Molecular Characterization of Pancreatic Simple Mucinous Cysts with GNAS Mutation: A Case Report and Literature Review.

SMC should be considered a differential diagnosis of pancreatic cystic lesions. Surgical intervention may be warranted based on findings.

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Prevalence of Fluid Overload in a Cohort of Patients with Acute Pancreatitis: Results from a Retrospective Tertiary Single-center Study.

The extent of fluid resuscitation was found to be strongly associated with the prevalence of clinical and radiological signs of pulmonary fluid overload. Furthermore, moderately severe and severe courses of pancreatitis were more frequently observed in excessively hydrated patients.

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Pancreatology

Genome-wide association study identifies FUT2 rs601338 polymorphism linking intra-pancreatic fat deposition to chronic pancreatitis.

This study identified novel genetic variants for pancreatic PDFF and confirmed related genes functions in the pancreas. These findings emphasize the need for regular surveillance of pancreatic fat deposition in the population with a high genetic risk based on FUT2 polymorphism, which could facilitate risk stratification and tailored therapeutic approaches for the primary prevention of CP.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Pancreas

Deep Reinforcement Learning: Revolutionizing Pancreatitis Progression Prediction.

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Sustained Response to Lanreotide in Metastatic Pancreatic Neuroendocrine Tumor.

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Pancreatology

Non-operative observational strategy for small non-functioning pancreatic neuroendocrine neoplasms: A feasible option?

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Letters&Replies

Letters to the editors and authors’ replies

Pancreatology

"Letter to editor: Defining pancreas delayed graft function - Advancement or premature standardization?"

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